Thought Leadership Program
Transforming Evidence into Action
Active Programs
Advancing the Use of Real-World Evidence in Coverage Decisions
Why it matters: Real-World Evidence (RWE) has significant potential to inform coverage and policy decisions, yet inconsistent standards and varying study methodologies make it difficult for payers to assess quality and minimize bias. Without greater clarity and consistency, opportunities to use real-world insights to improve outcomes, manage costs, and advance health equity may be missed.
Our work: AMCP is developing frameworks, educational resources, and multi-stakeholder collaborations to strengthen confidence in RWE and promote more consistent evaluation alongside clinical trial data, supporting transparent, evidence-based access decisions.
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Optimizing Biomarker Testing in Oncology
Why it matters: Despite established clinical guidelines, biomarker testing remains unevenly applied, leaving some patients without timely access to targeted therapies and personalized treatment strategies. Variability in coverage policies and implementation practices continues to slow broader adoption of precision oncology.
Our work: AMCP is engaging payers, providers, and other stakeholders to align coverage with evidence-based guidelines, expanding real-world evidence, and advancing practical strategies that reduce gaps in precision medicine adoption—helping ensure patients receive the right test and the right treatment at the right time.
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Making Patient Experience Data Matter in Coverage Decisions
Why it matters: Although the value of the patient voice is widely acknowledged, Patient Experience Data (PED) remains underused in formulary and coverage decisions. Many payers lack clarity on how to define, assess, and apply PED alongside clinical and economic evidence, limiting its impact on access decisions.
Our work: AMCP is clarifying the role of PED, increasing awareness of regulatory guidance, and developing practical tools to support its credible integration into P&T and coverage processes, advancing more transparent, equitable, and patient-centered care.
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Harnessing Artificial Intelligence to Transform Managed Care Pharmacy
Why it matters: Artificial intelligence has the potential to improve outcomes and operational efficiency, but payers need clear, practical standards to ensure AI tools are reliable, transparent, and equitable. Without shared guardrails, adoption risks inconsistency, bias, and unintended consequences in access and coverage decisions.
Our work: AMCP has launched initiatives focused on establishing standards and best practices for the use of artificial intelligence in managed care pharmacy. Through education, collaboration, and strategic partnerships, AMCP is helping guide responsible AI adoption that aligns with evidence-based decision-making and patient-centered care.
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Innovating Managed Care Strategies to Achieve Metabolic Health
Why it matters: The metabolic health crisis spans type 2 diabetes, obesity, MASH/MASLD, cardiovascular and kidney disease, conditions driven by shared underlying dysfunction and affecting the vast majority of U.S. adults. Despite advances in downstream therapies, managed care lacks a coordinated, upstream framework to integrate prevention, benefit design, and population health strategies that address root causes.
Our work: AMCP has launched a multi-year initiative to equip payers with practical frameworks and policy guidance that align coverage, prevention tools, and treatment strategies—supporting a more coordinated, root-cause-focused approach to metabolic health management.