Metabolic Health Initiative: Reimagining Managed Care Strategies

The Problem

Metabolic diseases drive rising costs and disparities, yet evidence‑based care remains inconsistent.

The metabolic health crisis is multidimensional—encompassing type 2 diabetes, obesity, MASH/MASLD, cardiovascular disease, kidney disease, and related conditions—all driven by shared underlying dysfunction (insulin resistance, inflammation, mitochondrial impairment).

Despite strong downstream work on GLP‑1s, MASH/MASLD, and access, managed care lacks a coordinated, upstream framework that integrates the multiple dimensions of the metabolic health crisis and identifies & operationalizes treatment & prevention tools (e.g., CGM, lifestyle interventions) across benefit design and population health.

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Impact

More than 88% of U.S. adults are metabolically unhealthy, driving a disproportionate burden of chronic disease and a $1.5T+ annual economic impact that is projected to rise without systemic prevention.

Breakthrough innovations—including GLP-1–based therapies, continuous glucose monitoring (CGM), and evidence-based lifestyle interventions—are rapidly reshaping care.

GLP-1 FAQs

Partner Opportunity: Spotlight Theater at AMCP 2026

AMCP will be having a high-profile 45-minute Spotlight Theater on metabolic health at the AMCP 2026 Annual Meeting on April 13-16, 2026 in Nashville, TN. This is a unique opportunity to be part of the first phase of this initiative and drive payer engagement with the new ADA guidelines.

Presented by AMCP with a distinguished payer panel, spotlights explore how plans are adapting benefit design and coverage policies in response to evolving ADA recommendations. An interactive Q&A with payers will discuss real-world implementation challenges and practical solutions.

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Appearance of theaters and titles subject to change.

Key Deliverables to Support Decision-Making

Education & Training

Including webinars, toolkits, podcasts, and meeting programming
Payer-Developed Frameworks

To support consistent, transparent metabolic health coverage decisions
Real-World Case Studies

With pilots in AMCP member organizations integrating CGM and evidence‑based lifestyle interventions.
Resources for Adoption

Published findings in JMCP and policy briefs on metabolic health policy and practice.