Chronic Kidney Disease Resources

Chronic Kidney Disease Resources

Chronic Kidney Disease is when the kidneys gradually get damaged over time and the kidneys are unable to complete functions such as removing wastes from your body, maintain blood pressure, and keeping your bones healthy. 

Science and Innovation Webinar
 

Webinar recorded on March 25, 2025*

Complement 3 Glomerulopathy (C3G) and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis (IC-MPGN) are two rare, chronic glomerular diseases caused by overactivation of the complement system resulting in severe kidney damage. Webinar topics include the prevalence, characteristics, and unmet medical needs of patients living with these diseases.

Signs of chronic kidney disease include:

• Itchy or dry skin
• Nausea
• Weight loss 
• Loss of appetite
• Fatigue
• Irregular urinating patterns
• Concentration issues
• Muscle cramps 
• High blood pressure 

Diseases and conditions that can cause chronic kidney disease include: 

• Type 1 or 2 diabetes
• High blood pressure
• Obesity 
• Heart disease
• Family history 
• Glomerular diseases
• Inherited conditions 
• Autoimmune conditions
• Severe infections 

Treatment of chronic kidney disease: 

• Following instructions when using medication
• Maintain healthy weight
• Avoid smoking

Journal of Managed Care + Specialty Pharmacy Publications

• Descriptive Study of the Economic Burden Among Patients With Type 2 Diabetes Mellitus, Chronic Kidney Disease, and Chronic Kidney Disease and Type 2 Diabetes Mellitus in a Large US Commercially Insured Population. Journal of Managed Care + Specialty, 2022, Dec;29(1):80-89.
• Costs Associated With the Administration of Erythropoiesis-Stimulating Agents for the Treatment of Anemia in Patients With Non-Dialysis-Dependent Chronic Kidney Disease: A US Societal Perspective. Journal of Managed Care + Specialty, 2021 Nov;27(11):1703-1713.
• Association of Dyskalemias With Short-Term Health Care Utilization in Patients With Advanced CKD. Journal of Managed Care + Specialty, 2021 Oct;27(10):1403-1415.

Additional Publications

• C3 Glomerulopathy: Understanding an Ultra-Rare Complement-Mediated Renal Disease. Heiderscheit A K, Hauer J J, Smith R J H. American Journal of Medical Genetics, 2022, Sep. doi: 10.1002/ajmg.c.31986.
• Clinico-Pathogenic Similarities and Differences Between Infection-Related Glomerulonephritis and C3 Glomerulopathy. Wada Y, Kamata M, Miyasaka, et al. Int J Mol Sci, 2023, May. doi: 10.3390/ijms24098432.
• Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein. Urban A, Kowalska D, Stasilojc G, et al. Frontiers In Immunology, 2021, Nov. doi: 10.3389/fimmu.2021.724361.

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*content (co-)developed by Apellis Pharmaceuticals, Inc.