The Academy of Managed Care Pharmacy (AMCP) supports policies that encourage the incorporation of cost-effectiveness considerations into health care decision-making. Cost-effectiveness analysis (CEA) is a method to assess the value of the clinical outcomes of a treatment relative to the cost. This type of analysis aligns with managed care objectives to optimize patient outcomes, maintain affordability, and encourage sustainability. CEA offers guidance to decisions about coverage and pricing to support managed care strategies—like formulary design, prior authorization, step therapy, and value-based contracting. Policies that promote cost-effectiveness help to ensure patients have access to treatments that deliver meaningful health outcomes at sustainable costs.