Vitiligo (vit-ih-LIE-go) is a disease that causes loss of skin color in patches. The discolored areas usually get bigger with time. The condition can affect the skin on any part of the body. It can also affect hair and the inside of the mouth.
Normally, the color of hair and skin is determined by melanin. Vitiligo occurs when cells that produce melanin die or stop functioning. Vitiligo affects people of all skin types, but it may be more noticeable in people with brown or Black skin. The condition is not life-threatening or contagious. It can be stressful or make you feel bad about yourself.
Treatment for vitiligo may restore color to the affected skin. But it doesn't prevent continued loss of skin color or a recurrence.1
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Journal of Managed Care + Specialty Pharmacy
- Prevalence and Incidence of Vitiligo in the United States: A Real-World Analysis. Gandhi K, Ray M, Borra S, et al. Journal of Managed Care + Specialty Pharmacy, 2021 Apr;27(4-a Suppl):S1-S152.
- Update on the pathogenesis of vitiligo. Marchioro H Z, de Castro C C S, Fava V M, et al. An Bras Dermatol. 2022 Jul. doi: 10.1016/j.abd.2021.09.008.
- The humanistic burden of vitiligo: a systematic literature review of quality-of-life outcomes. Picardo M, Huggins R H, Jones H, et al. J Eur Acad Dermatol Venereol. 2022, Apr 2. doi: 10.1111/jdv.18129.
- Patho-immunological mechanisms of vitiligo: the role of the innate and adaptive immunities and environmental stress factors. Faraj S, Kemp E H, DGawkrodger D J. Clin Exp Immunol. 2022, Jan. doi: 10.1093/cei/uxab002.
- The Immunogenetics of Vitiligo: An Approach Toward Revealing the Secret of Depigmentation. Dwivedi M, Laddha N C, Begum R. Adv Exp Med Biol. 2022. doi: 10.1007/978-3-030-92616-8_3.
- Prevalence of Vitiligo Among Adults in the United States. Gandhi K, Ezzedine K, Anastassopoulos K P, et al. JAMA Dermatol. 2022, Jan. doi: 10.1001/jamadermatol.2021.4724.
- A Literature Review Investigating the Use of Topical Janus Kinase Inhibitors for the Treatment of Vitiligo. Christopher White, Richard Miller. J Clin Aesthet Dermatol. 2022, Apr;15(4):20-25.
- Vitiligo Skin T Cells Are Prone to Produce Type 1 and Type 2 Cytokines to Induce Melanocyte Dysfunction and Epidermal Inflammatory Response Through Jak Signaling. Christina Martins, Laure Migayron, Claire Drullion, et al. J Invest Dermatol. 2022, Apr. doi: 10.1016/j.jid.2021.09.015.
- Post-Traumatic Stress in Vitiligo Patients: A Neglected but Real-Existing Psychological Impairment. Jia-Wei Liu, Yan Tan, Tian Chen, et al. Clin Cosmet Investig Dermatol. 2022, Mar. doi: 10.2147/CCID.S350000.
- Investigating the epidemiological relationship between vitiligo and psoriasis: a population-based study. Khalaf Kridin, Keren Lyakhovitsky, Erez Onn, et al. Arch Dermatol Res. 2022, Mar 25. doi: 10.1007/s00403-022-02358-8.
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1. MayoClinic. (n.d.) Vitiligo. Retrieved from https://www.mayoclinic.org/diseases-conditions/vitiligo/symptoms-causes/syc-20355912#:~:text=Vitiligo%20is%20a%20condition%20in,of%20skin%20color%20in%20patches.