Severe Asthma Resources

Asthma is a condition in which your airways narrow and swell and may produce extra mucus. This can make breathing difficult and trigger coughing, a whistling sound (wheezing) when you breathe out and shortness of breath.¹

For some people, asthma is a minor nuisance. For others, it can be a major problem that interferes with daily activities and may lead to a life-threatening asthma attack.¹ AMCP is pleased to work with Amgen Inc. to offer these resources to you.

Journal of Managed Care + Specialty Pharmacy

• The Effectiveness and Value of Biologic Therapies for the Treatment of Uncontrolled Asthma
  A Summary from the Institute for Clinical and Economic Review’s Midwest Comparative Effectiveness Public Advisory Council.  Journal of Managed Care + Specialty Pharmacy, 2019 May;25(5):510-514.
• Progression to Uncontrolled Severe Asthma: A Novel Risk Equation. Journal of Managed Care + Specialty Pharmacy, 2017 Jan;23(1):44-50.

Additional Publications

• Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe, Uncontrolled Asthma: Results from the Phase 3 NAVIGATOR Study. Menzies-Gow A, Corren J, Bourdin A, et al. Journal of Allergy and Clinical Immunology. 2021 Feb. doi: 10.1016/j.jaci.2020.12.050.
• EAACI Biologicals Guidelines-Recommendations for severe asthma. Agache I, Akdis C, Akdis M, et al. Allergy. 2021 Jan. doi: 10.1111/all.14425.
• Clinical Recommendations for the Management of Biological Treatments in Severe Asthma Patients: A Consensus Statement. Delgado J, Dávila I J, Domínguez-Ortega J, et al. J Investig Allergol Clin Immunol. 2021 Feb 17;31(1):36-43. doi: 10.18176/jiaci.0638.
• Prospects for severe asthma treatment. Calzetta L, Matera M G, Coppola A, et al. Curr Opin Pharmacol. 2021 Feb;56:52-60. doi: 10.1016/j.coph.2020.10.021.
• Managing chronic rhinosinusitis in severe asthma. Ramaswamy U S, Patel V A, Lee S E. Curr Opin Pulm Med. 2021 Jan;27(1):23-28. doi: 10.1097/MCP.0000000000000741.
• Applying personalized medicine to adult severe asthma. Tiotiu A. Allergy Asthma Proc. 2021 Jan 1;42(1):e8-e16. doi: 10.2500/aap.2021.42.200100.
• Asthma, severe acute respiratory syndrome coronavirus-2 and coronavirus disease 2019. Timberlake D T, Strothman K, Grayson M H. Curr Opin Allergy Clin Immunol. 2021 Apr 1;21(2):182-187.
• Bronchial Thermoplasty Induced Airway Smooth Muscle Reduction and Clinical Response in Severe Asthma. The TASMA Randomized Trial. Goorsenberg A W M, d'Hooghe J N S, Srikanthan K, et al. Am J Respir Crit Care Med. 2021 Jan 15;203(2):175-184. doi: 10.1164/rccm.201911-2298OC.
• Severe Adult Asthmas: Integrating Clinical Features, Biology, and Therapeutics to Improve Outcomes. Wenzel S E. Am J Respir Crit Care Med. 2021 Apr 1;203(7):809-821.
• Asthma control and psychological health in pediatric severe asthma. Griffiths D, Giancola L M, Welsh K, et al. Pediatr Pulmonol. 2021 Jan;56(1):42-48. doi: 10.1002/ppul.25120. Epub 2020 Oct 26.

Sponsored by Amgen Inc.

_{1. Mayo Clinic. (n.d.) Asthma. Retrieved from: https://www.mayoclinic.org/diseases-conditions/asthma/symptoms-causes/syc-20369653.}